• Welcome! The TrekBBS is the number one place to chat about Star Trek with like-minded fans.
    If you are not already a member then please register an account and join in the discussion!

Pharmacogenomic testing

Robert Maxwell

memelord
Premium Member
As some of you may or may not know, I work in the healthcare industry, specifically for a software company that deals in various kinds of healthcare-related applications.

A hot topic in the industry right now is pharmacogenomic testing. These are tests that are used to predict how patients will react to certain drugs. People with a given gene may react badly to a particular drug, or may require a lower initial dose, or may be better suited to use a different drug entirely.

Both CVS and Walgreens were planning to stock these tests, until the FDA stepped in and started asking questions at Pathway Genomics, who manufactures the tests. There are concerns over safety and accuracy. Both retailers have shelved their plans for the time being, pending the results of the FDA investigation.

Meanwhile, there is Medco, which is a massive pharmacy benefit management firm. Their intentions are to go full-bore into this kind of testing, and even advise insurance companies on what tests to require, which ones to cover, etc. However, they may have a conflict of interest because they fill an immense number of prescriptions--it might be in their favor to push tests that lead patients to more expensive drugs, which further lines Medco's pockets.

There's also the question of reliability. Having a gene doesn't necessarily mean anything. It's all a game of probabilities. You may have a gene and not express it at all. So, by that token, to what extent should your treatment be determined by the results of genetic tests?

How do you guys feel about all this?
 
I'm not too fond of everybody's genetic data being so widely available even despite any benefits it may have. It can be used for all sorts of purposes, even predicting behavior to some degree can be accomplished by genetic analysis.
 
Yeah. I would just object to it becoming mandatory in any way. I also think an insurance company shouldn't be able to penalize you for refusing to undergo genetic testing.

Basically, if you can take genetic tests and those benefit you, that's great--but I don't think it should be permitted to penalize you if the results are unfavorable.
 
I wrote a reply for this thread but I can't find the txt file now. :(

It was along these lines:

The spirit of insurance is that the misfortunes of a few are payed for by the many.

When insurance companies charge premiums in line with "assessed risk", then people at risk end up paying more.

As we get better at assessing risk, and predicting outcomes -- pharmacogenomic testing is one way of doing this -- then we can take this idea to it's logical conclusion: what people pay into an insurance fund in total is always slightly more than what they claiming back on it in total. In that situation, misfortune is no longer payed for by the many; people are forced to finance their way out of their own misfortune, plus some.

I'm not sure that's the future we want.
 
If you are not already a member then please register an account and join in the discussion!

Sign up / Register


Back
Top