I would settle for a full-out CGI remake of the existing animated series.
I mean, however good the actual storylines of TAS are (and at times, they are good), the actual show itself is typical of early 70's cartoons: Cheap crap.
A CGI remake of TAS would even get to keep the existing voice tracks (and possibly sound effects), so no dialogue would have to be rerecorded. And it could be made to look more like TOS - we have the technology right now to make fully realistic CGI representations of people, although CGI-TAS might not want to be quite *that* realistic.