In the episode Hard Time, I think it would have made much more of an impact if Miles O'Brien killed himself in the end. I mean, it would have sucked for Colm Meaney to leave the show, but whenever I watch that episode I always want O'Brien to really lash out at Bashir with all the barrels, and say that his "concern" for his frend's wellbeing is nothing more than "patronizing, condescending bullcrap" (or whatever euphemism for B.S. would be acceptable in that TV timeslot) and end the episode with him committing suicide.
Then the episode should end with no music at all.
Then the episode should end with no music at all.