Well, it doesn't even have to be as extreme as Blink of an Eye. Simply contacting new species, whether warp capable or aware of the interstellar community or not, alters/influences them. Any interaction with people at all is a form of interference. If you were truly non-interfering, you'd be isolationists. Heck, there's a point to be made that even just observation can potentially have affect. So own it a little bit, & avoid or mitigate the negative effects wherever possible or necessary imho The hard directive itself seems to only serve dramatic device, when we need to say "ordinarily we wouldn't be getting involved in this, but..." It's a way to add weight to a scenario, by implying taboo to their actions.