And to prove it, you'll take six syllables to say it! "Indefatigable" just strikes me as a silly, pretentious word that accomplishes nothing in six syllables that "tireless" can't accomplish in three syllables.
It sounds more sophisticated, I guess. Endurance says it in three, and sounds cool. Imagine the confusion if they ever had a USS Yuweses (or something along those lines).
Well, at least formal diplomatic meetings with new species would not be dull, assuming the ship has a corresponding emblem that's proudly displayed everywhere on board ...great conversation starter.
Apparently the crew of the most recent HMS Beaver were not keen on the name, for potentially obvious reasons. Also rather odd that the Royal Navy would use the name when beavers have been extinct in the UK since the 16th century. Then again, there's also been HMS Beavers since the 16th century, so...
Europeans are also weirdly fond of lions in national symbols and coats of arms, and in most European countries, those haven't been around for a lot longer than just 400 years.
I. for one, would not hesitate to board the USS Furries; oh, the crew names... USS Johnson is an obvious one. Might sound innocuous enough at first, but... USS Llanfairpwllgwyngyllgogerychwyrndrobwllllantysiliogogogoch. You're gonna need a bigger saucer section. Or wrap it around like a long footballer's name on the back of their shirt. And the Universal Translator will never forgive you. Or the crew members who have to put their teeth back in after every attempt to say it. This is definitely my kind of thread.
<On planet when flowers start attacking>: Ensign Redshirt to Llanfairpwll... Llanfairpwllgwyng.... JUST BEAM US UP! NOW!
One more, since my silly brain's on a roll. Imagine a naming ceremony gone wrong. Cheap bottle that breaks as it's gripped to be swung. "I hereby christen this vessel..." And thus the new Federation flagship becomes the USS AAH My Bleedin' Hand. :-p