"That guy's like a Kirk sundae with Trip Tucker sprinkles." - Boimler Had to pause I was laughing so hard.
First, a little bit of nitpicking: It's actually: "Sir, I protest! I am NOT a Merry Man!" (Sorry, as a Worf fan I couldn't let that be misquoted ) Others I like are: Spock: "Logic is a twittering little bird, chirping in a meadow. Logic is wreath of pretty flowers that smell bad. Are you sure your circuits are registering correctly? Your ears are green!" (I, Mudd) Kirk: "You're suffering from a Vulcan mind-meld, doctor." McCoy: "That green-blooded son of a bitch! It's his revenge for all the arguments he lost." (TSFS)
"If all of your little 'advertisements' aren't purged from our system by the time I return from the Gamma Quadrant, I will come to Quark's and believe me... I will have fun." [Maj. Kira]
"Allamaraine, count to four. Allamaraine, then three more. Allamaraine, if you can see. Allamaraine, you'll come with me." ("Move Along Home") "Lovey-dovey. Bonk, bonk on the head. Bonk, bonk! Bonk, bonk!" ("Miri") Spock: "We'll never reach an Earth base with him aboard, Jim. You heard the mathematics of it. In a month he'll have as much in common with us as we'd have with a ship full of white mice." ("Where No Man Has Gone Before")
Spock: I have been... and always shall be... your friend. (TWOK) Makes me cry every time. And, of course, the end of STVI: Uhura: Captain, I have orders from Starfleet Command. We're to put back to Spacedock immediately... to be decommissioned. Spock: If I were human, I believe my response would be... go to Hell. If I were human. Chekov: Course heading, Captain? Kirk: Second star to the right... and straight on till morning.
Agreed, a great line. Though I also would have loved Garak to come up with a demolishing and witty retort to that.
A favorite of mine... "..." -Adm. Thomas Henry, "The Drumhead" He doesn't say a word. He doesn't have to.