I thought I had the correct Voyager answer right on the tip on my tongue until I realized that I was thinking of Tom's "Nice mustache" line to Marseilles and I couldn't think of any other likely scenarios that it might have been uttered during the series. Then I thought, with deepest apologies offered in advance, Klingon's quote. Klingon= devious, tricky. Bingo, Way of the Warrior yet again, Worf introducing himself to Kira. Almost forgot, I've got to keep things moving! Okay, this one's not necessarily a softball, but I think it should be picked off pretty quickly. "Harry, is this possible"?
The Clown in The Thaw! It was regarding Janeway's proposal. Loved Michael McKean in that role. There needs to be more movies with Michael McKean, Dan Akroyd, Christopher Guest and Fred Willard. Ok, next clue - a screen capture:
Is this the Enterprise episode where the ship is trapped in what looks like the middle of a swimming pool? (Did I dream that?)
^Maybe you're thinking of the area around that Suliban space station & cluster of hive ships? If so, you'd be correct! Nevertheless, Leadhead intuited correctly first, it is the scan from the ENT pilot Broken Bow (though I couldn't recall the Klingon's name). Congratulations on your guess, the scan was only onscreen a brief moment! Your clue, Leadhead!
Lady T'Anna, that was my guess too. Oh well! I've been coming up with a lot of dead ends! Revised list: Was it Bashir?