Are there no Ferengi drug dealers?
I bring this up because, in "Little Green Men," Quark seems surprised by both the concept of tobacco and cigarettes as well as the idea a product would be sold that's both addictive and dangerous that people would buy for pleasure.
There's also the question as to whether smoking among humans (and anything else affected by tobacco) as a vice would still be a thing in the 23rd/24th century. Raffi is shown smoking something in Picard but beyond that there are "no smoking" signs in the Enterprise transporter room in Wrath of Khan and Search for Spock, indicating some people still smoke something and the transporter room is one of the places you can't. Then you think about whether there would still be huge tracts of land growing tobacco in the 24th century. But, on the other hand, Picard has an entire vineyard for his wine. So using land on Earth for crops to produce wines and spirits seems to be a thing, and it wouldn't be a huge jump to get to tobacco.
I bring this up because, in "Little Green Men," Quark seems surprised by both the concept of tobacco and cigarettes as well as the idea a product would be sold that's both addictive and dangerous that people would buy for pleasure.
QUARK: What is that disgusting smell?
NOG: I think it's called tobacco. It's a deadly drug. When used frequently, it destroys the internal organs.
QUARK: If it's so deadly, then why do they use it?
NOG: It's also highly addictive.
ROM: How do they get their hands on it?
NOG: They buy it in stores.
QUARK: They buy it? If they'll buy poison, they'll buy anything. I think I'm going to like it here.
It seems interesting Quark would obsess about the choice of being an arms dealer but never considered the profit in selling drugs. Especially since he owns a bar and presumably understands the appeal of alcohol and other similar concoctions.There's also the question as to whether smoking among humans (and anything else affected by tobacco) as a vice would still be a thing in the 23rd/24th century. Raffi is shown smoking something in Picard but beyond that there are "no smoking" signs in the Enterprise transporter room in Wrath of Khan and Search for Spock, indicating some people still smoke something and the transporter room is one of the places you can't. Then you think about whether there would still be huge tracts of land growing tobacco in the 24th century. But, on the other hand, Picard has an entire vineyard for his wine. So using land on Earth for crops to produce wines and spirits seems to be a thing, and it wouldn't be a huge jump to get to tobacco.

