I think the Civil War comparison is only half right. If you didn't like Civil War because of the number of characters being juggled, then obviously, you won't like this any better. If you didn't like it because of the general style, then maybe also (although Infinity War was not exactly the same in that sense either - this is a much more epic, and more brutal story).
But most of the other complaints I remember seeing about Civil War don't really apply to this one, imo. I love them both, but I think this one is definitely even better, smoother, more polished and will probably be more accessible to more people.
The only other issue I can think of that the two movies really do share is the fact that much is dependant on your knowledge of ongoing storylines/character arcs. This movie really is the culmination of this Cinematic Universe, so if you go in expecting anything even remotely similar to a stand-alone story, you'll not be happy.
As to the movie itself - easily the best marvel movie yet. Probably my new favorite superhero movie, A+ all the way.