Well, the new Hulk status quo literally just happened with his latest issue last week. And it was a #1, a good jumping on point. So picking up most books now is probably a great way to start, as they all take place 8 months after Secret Wars so they sort of have to get new (and old) readers up to speed on the status quo. Other than that, Falcon is now Captain America (Steve Rogers is old) and Jane Foster is Thor, and Inhumans are the new X-Men. The rest is easy to figure out along the way.