Comparing Kirk vs. Kruge and Sisko vs. waves of Klingon warriors, I'll pick Sisko. Sisko kicked the crap out of mirror Bashir. Does that count?
Shirt-less Kirk beats all versions of Sisko. Bearded Sisko beats clean shaven Sisko. Shatner's priceline daughter (nu-Penny) beats and pwns nu-Kirk. Estrogen augmented pregnant Kira beats enraged nu-Spock.
Kirk vs. Kruge was not Kirk in his prime...he was past his Kirk Fu days at that point. And did Bashir ever exhibit or claim to have five times human strength? All augments are not necessarily created equal, especially as Bashir was the product of black market augmentation three or four hundred years after Khan's time.
No, but he was never in a situation where he could have used his strength once his enhancements were public knowledge. Every time he could have tried beating someone up happened before the lid was blown on his secret. Sisko alluded to his physical abilities being superior when he was talking about playing the Vulcans in baseball. --Sran
^Perhaps Kirk has the chops to beat Sisko on his own, but Sisko would do well against ten Kirks in an army of Kirks.
^I'm picturing Sisko facing down an army of Kirks and telling the Prophets to "stop those Kirks" before each one disappears, leaving behind a mound of hair pieces. --Sran
Sisko is choking Kirk when Kirk's toupee flies over and lands by Spock's feet. Kirk says to Spock in a raspy, angry voice, "PICK IT UUUUP!"
The Sisko. It would be a long bout but Sisko is a bit more athletic and punched out Q. His omnipotent "donkey" didn't see that coming.
Kirk: "Can't ... you see ... THAT .. you can never ... WIN !!!! Sisko: "I ... MOST ... CERTAINLY ... WILL !!! Kirk: "Sabataage."