The concurrent with TNG part doesn't really give me that impression so much--they've been saying stuff like that since book 1 to try to get people interested in the series. (From the universe of Star Trek: The Next Generation...) However, the "picking up at a point where there have been significant changes" certainly sounds like it could be a reference to Destiny...either that, or there have been significant changes to New Frontier since the last book? **shrugs** Well, at least we'll be captivated...
Well, there were some pretty dramatic events in Treason. But, that's not to say that I don't think this one is Post-Destiny, because I do.