http://www.hulu.com/watch/19313 The Last Voyage of the Enterprise, one of the best Trek parodies ever, from the golden age of SNL.
Beavis & Butthead Embedding seems to be disabled for this video. Here is link. http://www.youtube.com/watch?v=Rh17jKL0DfA Hawaii 5-0: http://www.youtube.com/watch?v=70xHGhXwfPY representative from Oregon discusses Klingon politics http://www.youtube.com/watch?v=Tb8jy2bEt-M Matts Weather and Zefram Cochrane.wmv http://www.youtube.com/watch?v=7ggXCKbJl20
Also one early episode of South Park was a direct parody of Dagger of the Mind, with brainwashed kids at the planetarium saying "I love my work." And another one was a parody of Miri, where the kids made all the grownups get arrested by telling the police they molested them, and then a guy's car breaks down in the town and he ends up giving a Shatner speech to them. "Your...birthgivers!" Then there was that episode of Beavis & Butthead where Butthead dreamed he was captain of the Enterprise and ordered Troi to take her clothes off. http://www.youtube.com/watch?v=Rh17jKL0DfA And pretty much every sitcom which has a nerdy character has had some kind of Star Trek reference. I vaguely recall an exchange on Drew Carey where two nerds are debating whether Dax is desirable considering she has an 'old man worm' in her belly. And Family Guy has probably done a zillion cutaway references to it. Shatner is heavily involved in the first episode, and Stewie recalls his ancestor 'Quark Griffin'. Odo: "I could turn into a snake and swallow you whole." Quark: "Yeah, why don't you change into something with a personality." Upright Citizens Brigade had a skit about Little Donny, a child with a medical condition where he had a very large penis, and he had an obsession with Tuvok.
And of course Seinfeld had a bunch of ST references. [yt]http://www.youtube.com/watch?v=9NVV7x9su_w[/yt] http://www.youtube.com/watch?v=9NVV7x9su_w
In addition to the Space Shuttle Enterprise, there's now the VSS Enterprise, Virgin Galactic's suborbital spacecraft.
In Criminal Minds, the IT teach, Garcia made a reference/joke about being doomed "as in Star Trek red shirt doomed" It was the same episode that Jonathan Frakes guest starred.
There's also this little gem, which means that Matt and Trey aren't just Trekkies, they're fans of Zephram Cochrane: Stan: You know, somebody once said, “Don’t try to be a great man, just be a man.” Jesus: Who said that? Stan: You did, Jesus. Jesus: You’re right, Stan. Thank you, boys! Kyle: Wow, did he say that in the Bible? Stan: Nah, I saw it on Star Trek. -South Park, “Damien”, during the boxing match between Jesus and Satan