Fooling his sense would be difficult.
Blasting his brain with radiotelepathic countermeasures that forces him to misunderstand when he is seeing and smelling would be much easier.
Of course even easier than that would have been to have brainwashed hypnotic triggers in Wolverines mind to ignore LMDs and believe that they are real people.
Of course, his senses wouldn't have any brand recognition that would kick in fast enough before he started ignoring the LMDs that he couldn't tell the difference between S.H.I.E.L.D. LMDs, Chinese LMDs or Hydra LMDs, and they would all seem equally like real people and not robots... Unless it wasn't Robots he ignored, but a precise trigger sense to create different degrees of invisibility or camouflage, like X-23 has a trigger scent that creates a melee killing rampage.