Re: Imagine the Enterprise, over again!
Hmmm, I'll have to think abit. I would be more inclined to go "clean sheet" and not tie myself to saucers, nacelles, or any of that stuff. My first inclination would be to go for something based a little more on current thinking regarding possible future tech. The tough part would be to make something iconic like the TOS design that separates it from the crowd of current day sci/fi ships.
Baby, you and me were never meant to be, just maybe think of me once in a while...