I found the interaction between Garfield and Stone to be uncomfortable at times. The whole "well you can't have a pretty wee nose and you can't have deep soulful eyes" scene was cringe inducing. That's just how I saw it at the time - though I see I'm in the minority.
The film's saving grace, honestly, was Gwen's fate. By that stage I felt her and Peter had gotten away with too much without consequence.