Never understood the two takes label. So Sir Patrick, Dorn, Sirtis, McFadden, Burton, Spiner or himself when in shot never messed up their lines? lol.. Based on some Youtube videos, seems they needed more than two takes often than not.
That said I think even the episodes directed by him and not the films are the amongst the best in quality, and that's no coincidence IMO. I think though as Picard was the "star" (it's an ensemble show but then to many the Captain is the main character), he's naturally become a global actor.