Joel McHale as Captain Winger
Danny Pudi as the android First Officer/Science Officer ABED
Gillian Jacobs as Communications Officer Perry, who's always accidentally hanging up on people. She's the worst.
Yvette Nicole Brown as Security Chief Bennett
Donald Glover as Conn Officer Barnes
Alison Brie as Dr. Edison
Chevy Chase as curmudgeonly Chief Engineer Hawthorne. He's streets ahead.
With Ken Jeong as Chang, a weird alien who lives in the ships Jeffries' Tubes
and Jim Rash as Starfleet Admiral Pelton