I've never noticed the problems with Reed or Sopek, but looking at the image of Sopek on Memory-Alpha
it does look very "splotchy." I'm not sure about the Reed lipstick issue though, I've never noticed it and nothing seemed to stand out in the TrekCore screencaps.
That said, when rewatching on blu-ray, I noticed that some of the Andorian makeup jobs were pretty poor as well. There was one (I don't remember who it was exactly, maybe the SO who appears on the viewscreen in "Proving Grounds") where the makeup around the eyes was quite bad, like they forgot to apply the blue eyeliner, so he had pink rings around his otherwise blue face. It definitely brought be out of the episode, given that he was in several closeups.