A is for the Adelphi, the Federation starship involved in the disastrous Ghorusda disaster sometime prior to 2366.
B is for Barclay's Protomorphosis Syndrome.
C is for Cryonics, a kind of fad in the late twentieth century.
D is for Darnay's Disease.
E is for Enterprise. USS Enterprise, CVN-80. Ford Class nuclear next-generation carrier. In pre-production now. Her ship's log is empty. Awaiting greatness.
F is for the Farragut, a Nebula-class starship that was one of three vessels ferrying rescued Enterprise-D survivors from the surface of planet Veridian III.
G is for Glommer. Tribble predator.
H is for Hydrogen inside the stars studied by Federation starships.
I is for Interphasic Organisms.
J is for Jaris, governing Prefect of Argelius II in 2267.
K is for Khitomer Accords.
L is for Lieutenant. The apparent rank of 90% of Star Fleet.
M is for 'MALTZ! JOL YICHU!'
N is for the Norpin V Colony.
O is for Omicron Ceti III.
P is for Perrin, the second human wife of Ambassador Sarek in the Prime timeline and his spouse at the time of his death in 2368.
Q is for Quantum torpedoes. Fire!
R is for the Reliant's shields. They're dropping. Raise them!
S is for Spock's bathrobe.
T is for the Talos Star Group.
U is for Ugly Bags of Mostly Water.