A is for the Altair Sector of the Alpha Quadrant.
B is for Bibi Besch.
C is for the Canamar prison ship of the mid-22nd century.
D is for Dickerson, Security Officer.
E is for the Enterprise-A, the second Federation starship to bear the name and launched in the immediate aftermath of the Whale Probe Crisis of 2286.
F is for Führer John Gill.
G is for Gomtuu. The last of her race.
H is for Holliday. Doc Holliday.
I is for Ingraham B.
J is for Janeway. The surname of a high-ranking Starfleet admiral and also his daughter, one of the most famous starship captains of the late 24th century.
K is for Klingon Tea Drinking Rituals.
L is for Love, strange love a Starwoman teaches.
M is for Mars, explored by human astronauts as early as the year 2032 and possibly even ealier.
N is for Nausicaan Pirates.
O is for Out there, Outer Space. Where the great adventure begins.
P is for President Abraham Lincoln, a personal hero to James T. Kirk.
Q is for the Quest to locate Sha-Ka-Ree.
R is for Romulan Ale, illegal but sometimes used for medicinal purposes.
S is for Selar. How I wish she was in more episodes.
T is for Tal, Romulan subcommander and second-in-command of the modified Klingon D7 cruiser equipped with an advanced cloaking device in 2268.
U is for Ultimate Computer, hyperbolically predicated of the M-5 Multitronic Unit.
V is for ventral phasers. Keeps Enterprise's curvy backside from being shot at.
W is for West. Starfleet Colonel West. Mastermind of Operation Retrieve and co-conspirator in the plots to assassinate both Gorkon and the Federation President.
X is for X as in Roman numeral ten, as in the Terra X colony which became known as Terratin.