Well, I'll be rooting for the Seahawks for as long as they last, mainly because of Pete Carroll's USC connection. Harbaugh seems to have a real hard-on for Pete since the USC/Stanford days. Probably because of those ass kickings he took from SC in the Rose Bowl back when he played for Michigan.
The 49'ers though, do look like they are on a mission. But this time they are playing a defense that is just as good as theirs.