Well, in UT canon, the USS Endurance is assigned to the Andromeda Galaxy in the series The Endurance of Jesse Yeager..
Not sure if that happened before or after this, chronologically, however.
Though the odds of those two ships making contact with one another in the entirety of an unexplored galaxy is beyond remote.
It looks like I've missed that one. Very true though, it is a pretty big galaxy.
I'm easy either way, though.
Commander Austin Harris, First Officer, Deep Space Nine (by FltCpt. Bossco)
8.01 - Darkest Before Dawn
(Chapter 8 added, 12/09/2015)