I don't see why it even matters.
Let's say they give us another Trek series. To be profitable it is going to have to look good, much better than the previous series. Sharper dialogue, stories that move faster, more edge. It's going to be different whether it's the Prime universe or not.
It wouldn't matter in the slightest.
I really think that a lot of fans who say they want a new show set in the Prime Universe are really saying either that they want a continuation of their favorite Berman-era show or that they want a spin-off with some of their favorite characters, probably even played by the same actors. Neither of those is going to happen, though.