Have you watched the TV Series Andromeda? The ship is personified in a female character (The actress is sexy, and dressed in a tight outfit, but, it's not played for sexiness all that much). I personally enjoy the first 4 (of 5) seasons, others will say it went downhiill anywhere from S2 onwards. You might like Rommy's character quite well.
Can't really think of any movies offhand
One Day I hope to be the Man my Cat thinks I am
Where are we going? And why are we in this Handbasket?