I've mentioned her before on another thread, but I think Dina Meyer would be a great Captain. I don't know why, but I always envision her with Trill spots.
I'd also love to see Alex Kingston in the centre seat. I think she would play a very interesting Andorian.
Commander Austin Harris, First Officer, Deep Space Nine (by FltCpt. Bossco)
8.01 - Darkest Before Dawn
(Chapter 8 added, 12/09/2015)