One of the problem with a 25th century show would be that the technology would be so far advance that it would be difficult to have any drama on the show, things would be too easy for the crew.
My problem with this is the assumption conflict within stories of Star Trek
are to be solved by technology. That has been too often the case. But I find it a sign of very lazy, bad writing that so many stories ended up structured that way. I remain far, far more interested in conflict between people and ideas.