I'd still like a Titan series. Live action or animated. And yes, with Frakes, Sirtis and Russ
Tuvok? I would hope that if is there is a Titan series, it would be completely disconnected from the Titan depicted in the books. Give the production team a fresh ship (other than Riker and Troi) to create their characters and stories.
a Starfleet medical ship struggles to keep up with the sick and wounded.
Almost any of these basic premises could fit easily into the 23rd, the 24th, the 25th or the 39th centuries.
Given the advances in medical science shown on the series, the centuries would change a medical story quite a bit.
One of the problem with a 25th century show would be that the technology would be so far advance that it would be difficult to have any drama on the show, things would be too easy for the crew.