Exactly my thoughts.
was a (fictional ship) that saw a mutiny because of the sadistic nature of its first officer, everybody aboard the USS Defiant
(NCC-1764) got killed because of Interphase Madness before the ship vanished in interspace and Sisko's USS Defiant
was destroyed at the beginning of ST VIII. Much better.
I think HMS Reliant
is a fictional ship, too (no disasters to report here), but USS Reliant
perished at the end of ST II.
In general, it doesn't seem to be such a great idea to serve on a Federation ship whose name ends with "...iant".