Am I the only one who gets teared up at the very last shot of DS9?
ETA: I just watched the last ten minutes of it again. *sad*
I do. Then I hug my son.
Other top contenders (I can cry easily):
TOS: "Let me help" speech.
"It's me" speech from Inner Light
"It's not linear" speech from the Emmisary
"I'm a good tailor" speech from The Die is Cast
End of The Visitor
"I need a miracle. Bajor needs a miracle"
"Maybe a year. Maybe yesterday."