It's almost impossible to drive and shoot at the same time I don't know how we're supposed to be able to do it. I don't think the cars handle "too" bad though they do have some odd quirks here and there. Aiming, period, is hard for me as the aiming radial is too light colored and too easily blends into the background so I really struggle to aim most of the time, it also seems there's no "auto lock" feature with an ability to scroll through targets.
Been having fun with the game, I'm not too far through the story mode, just finished the mission with Michael and retrieving his son from the boat. I like the Michael character, hell even Franklin's pretty cool. And thank God I don't have my friends calling me all of the time bitching about going bowling.