Prime timeline, alternate timeline, still another alternate timeline, the Mirror-verse...whatever. I want good stories and good characters.
Having said that, it also depends on what one means by the prime timeline? Do you consider official novels to be canon--in which case a big chunk of the Federation was destroyed by the Borg, Andor seceded, but the Borg themselves are no more. Is STO?
My concern is with the increasing trend towards wars, explosions, roller-coaster rides and the like. Not that wars cannot make for great stories! The Dominion War included some excellent episodes! But frankly stories about what happens when we're not fighting for our lives against vast armadas of terrifying starships has a lot more resonance with my life. Can't even remember the last time someone succeeded to destroying a planet.