Very curious as to what kind of relationship this series will have with the films. There's every reason to think A-list Superheroes will appear on screens at some point, or be the subject of discussion, or appear offscreen during engagements. I would expect to see Samuel J. at least once.
Also, since Black Widow and Hawkeye are human, they're more likely to appear as they would spend the most time with S.H.I.E.L.D.? Eventually, RDJ will have
to appear. My guess would be as Tony, not Ironman.
I hope this series is great and that it lasts for a while. It's been a while since a watchable sci-fi series was on broadcast TV.