We had the gamma quadrant in DS9, , Delta in voyager , the alpha is more or less been covered so discover the beta quadrant.
go beyond on the far side of the klingon and romulan borders and start again.
Unexplored space is where the writers need it to be. Take a good look at this picture
of the center of the galaxy and tell me there's no opportunity for good story telling anymore.
And BillJ, what's wrong with BSG? I think it fits very well somewhere between Berman Trek's 80's sitcom style with almost static camera's, and J.J's frantic over-the-top actionmovie lensflare sequences.