Re: Avengers 2 News, Rumors, Etc. Pictures until release...
I think Marvel would shy away from using it because people would think it's an odd Spiderman ripoff (regardless of what Sony would think). I don't think Spiderwoman is iconic enough. Black Widow, Captain Marvel, and maybe a few others would be smarter choices for a female franchise lead.
When on Romulus, Do as the Romulans