But don't forget to add 'new writers' and 'new story' to that. Otherwise, some people will assume going back to the Prime timeline only means repeating the new alien of the week theme.
Good points about the necessity of new writers and new stories. I'd also add to that new ideas and concepts would be necessary too. Though, there does have to be some balance in a new tv series between a series and/or seasonal arc and standalone episodes as well as a balance between "seeking new life and new civilizations" and seeing familiar species such as Romulans and Klingons. Exploring new directions for 25th century Romulans, Klingons, etc. to take could be just as interesting to viewers as exploring whole new alien civilizations so a good variety of different types and styles of episodes would be essential. Also, there's the danger of just becoming Star Trek: The Next Next Generation to be avoided, but despite some similarities being unavoidable the general trope is avoidable.