Id MUCH prefer a 25th century show, than ANYTHING, movie, show, puppet show, set in the NuTrek universe.
With one exception:
Lets see a Federation dealing with the destruction of Romulus, and refugees from the fragmenting empire.
Kirk and Spock are dead. DEAL WITH IT.
If you don't want Kirk and Spock, then you don't actually want what actually matters in Star Trek.
You may aswell have a new sci TV show based on a new universe, worlds, races, characters, gadgets etc.
Because anything else with a Star Trek label is a diluted spin-off which is doomed for failure.