I have to admit, my reaction to the poll questions is: Is this a joke?
Unless we're talking Voyager from Endgame with all the fancy upgrades (which God knows, the Defiant and Enterprise would both be first in line to get similar upgrades once the Core of Engineers got a chance to play with Voyager), the E-E would probably be able to take both the Defiant and Voyager at the same time and still win. Heck, throw in the Titan to, just to make it almost fair.
Speaking of which, this DID make me realize --- why the heck didn't we see the E-E in Star Trek Nemesis have "Voyager-Esque" upgrades? Did someone forget to watch Endgame ? =(