A is for Alpha III, site of an historic tribunal reinforcing the concept of individual freedom.
B is for Botany Bay.
C is for Ceti Alpha VI. Victim of a gigantic explosion.
D is for Da Doomsday Machine.
E is for Eymorg cleavage.
F is for Fat Federation Captains.
G is for Garak. Plain, simple Garak.
H is for Hole in space.
I is for Iyaarans.
J is for Janeway's Jugs.
K is for Klingon Emperor. The clone of Kahless was the first one since the 21st century.
L is for Leonard Nimoy.
M is for the Matter Antimatter Reaction Chamber. Aka, the big giant lavalamp.
N is for Negaton hydrocoils.
O is for the Ophiucus star system.
P is for the Picard Manuever. Both of them. Required study at Starfleet Academy.
Q is for Q's quest to study humanity.
R is for Regulan Blood Worms, reminiscent of Earthers, all but Kirk.
S is for Satarran mysteries.