I wonder if they will tame Barrys powers down to the Wally level back when his series originaly started. Cant exceed the speed of sound, cant vibrate through things, has to eat constantly. A full blown Flash is a very powerful creature. I also hope the Speed Force figures into things. This would allow them to actually introduce dare I say Wally at some point in the series.
Captain Cold, Heatwave, The Top, Captain Boomerang, Mirror Master, Reverse Flash and The Eradicator(no not the Superman one) top my list of villians to see.
Colonel Computron, Big Sir, and Rainbow Raider need never appear.