Re: Joss Whedon's S.H.I.E.L.D to ABC!
I imagine there are other SHIELD teams as well as rival agencies. Hydra, perhaps, could make for a good recurring villain. The same with whatever remains of the Ten Rings syndicate and other such enemy groups. I really hope they work out a way to have Mutants at some point, as that is a pretty big part of the Marvel Universe to have to leave out.
"There is no reason why good cannot triumph as often as evil. The triumph of anything is a matter of organization. If there are such things as angels, I hope that they are organized along the lines of the Maffia." - Winston Niles Rumfoord.