The most jarring bit for many people not conversant even in passing with the earlier iteration of the novels is the Klingons and their urgent search for a particular substance on the planet.
Basically at this time some authors had established that without a kind of drug Klingons were incapable of controlling their violent urges, and the crew of this ship had run out some time ago. It's like a less intense version of ketracel white basically.
I don't remember any books asserting that about the Klingons. And once you get to the end of Doctor's Orders
, you'll see that things aren't always what they seem.
To the best of my recollection the idea appears first in ... http://en.memory-alpha.org/wiki/Timetrap
and I assumed that DD picked up on it and made use of it.
Sadly while the book is not unreasonably priced for Kindle I've already been a bit too indulgent (two back stock books plus pre-order for DWards new one out next week) so I can't pick it up right now to double check.
Oh and I forget to say earlier, thanks to Therin. I should have known that if there were any neat bits of trivia to share it would be you who would have it.
I love my fellow Trek addicts.