^Pyg and Toad were introduced into Batman comics by Grant Morrison in 2007 and have been major players in his run on Batman. Pyg in the comics
is a much more twisted figure who mutilates people in horrible ways.
Apparently the comics' Mr. Toad is "a mutated frog man." The way he was animated here, he clearly wasn't in a mask, and Pyg did refer to him as an amphibian. I don't think we know enough about the BtB universe at this point to say what does or doesn't fit in it.