As a reader I'm all for change. That's probably the biggest part of my preference to the 24th century novels - you get the impression that things are actually going somewhere.
I have trouble reconciling this with not wanting characters to be killed off though...
Wasn't there a Spock quote about change in TUC, 'nature abhors a vacuum'? Cant remember now.
I want the characters to continue on as they would in 'real life'. People move on to other things, they grow, they die. I'm good with that. I may have an attachment to the characters but can accept what happens as long as the story is a good one.