I have family members who are and have been on SSRIs. They work well for a while then your brain adjusts to them and they stop working, and quitting them cold turkey leads to a severe crash. They're not addictive the way heroin is addictive but they certainly cause dependencies.
SSRIs are awesome if the cause of your depression is chemical. But modern psychiatry jumps to the conclusion that they are, and when they're not, they're not helping at all. They're just a long term crutch that keeps people from dealing with the real cause of their depression (Except in the case where it's chemical).
If Barcalay existed today nobody would reach out to him and try to help make him more socially comfortable. They'd just give him SSRIs, and he would have never learned the social coping skills he did by the end of Voyager.