Re: So what characters do you think have changed the most?
Picard is close to completing his journey.
He is married to the woman the show set up as then resisted using as his probable romantic interest and he has overcome his dislike of children via Wesley.
His priorities have changed - he has allowed himself to be conflicted in his career by his relationship with Beverly and he has become a father. He is now considering leaving Starfleet for his families sake.
I'd say that's change...
Soon oh soon the light, Pass within and soothe this endless night, And wait here for you, Our reason to be here...