^ Which is why hologram or drone ships could've made a difference for the Federation. With drones doing the bulk of the fighting the human resources could've been put to work building more ships or retrofitting existing ones.
You look at androids and holograms in Trek. They can think and reason. Uploading fight strategies or combat directives could have given a tactical advantage in combat. Computers can process data and react faster than people. After every dominion encounter the data gathered could've been uploaded to drone ships already existing catalog of data.
A flesh and blood command officer like Sisko, or Jellico could have been present to help add variety to battles. I mean we have computers today that can think and perform tasks assigned to them. More advanced computers are capable of reasoning.