Interesting question, interesting choices. I would say that Alyson Hannigan, born in 1974, is way too old for the part of Colt. Don't get me wrong, she looks great, but Colt was about 20 in "The Cage," and American Pie
was a loooong time ago.
Michael Hogan as Boyce would be fascinating - I know him mostly from BSG, and playing a wise, caring mentor would be quite different from that role!