I still maintain that whatever happened later, the end of the first season was very anti-climactic. I don't even remember the details beyond Sylar getting stabbed and crawling off into the sewers. Honestly, I'd rather they let him blow because that post apocalyptic future episode was *way* more interesting than what they ended up doing.
As for Lost...I have tried to watch it again a few time. Never got much more then five episodes in before I lost interest. It's not because I know how it'll turn out, it's because there character on their own were never that interesting for me. Don't get me wrong, there are some very strong characters and good performances, but it's not enough to sustain my interest. This show has no "Londo & G'Kar" to hold it all together.
Actually, now that I think back, while individual performances were very good, the chemistry on that show was pretty damn poor in some very vital areas. At least that the impression I'm left with.