No. The creators' intent remains intact if I accept it as is: their imagining the late 20th century evolving as they referenced onscreen regardless of how our history actually played out. I don't have to throw out anything other than all the things later Trek did to knowingly contradict what had been referenced on TOS.
In that I'm quite happy with the mileage I'm getting.
By "intent" I mean the the show in general, not the details of each episode. As I've said before, they saw Star Trek as our future not an alternate reality and would probably be more than happy to ignore their "predictions" if Star Trek (TOS if we must) had lasted into the late 20th Century.